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TTHX 1114

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Drug Profile

TTHX 1114

Alternative Names: NM-141; TTHX-1114

Latest Information Update: 28 Dec 2023

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At a glance

  • Originator Florida State University
  • Developer Florida State University; Trefoil Therapeutics
  • Class Eye disorder therapies; Fibroblast growth factors; Recombinant proteins
  • Mechanism of Action Fibroblast growth factor replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Fuchs' endothelial dystrophy
  • Phase I Corneal disorders
  • No development reported Corneal ulcer

Most Recent Events

  • 28 Dec 2023 No recent reports of development identified for preclinical development in Corneal-ulcer in USA (Topical)
  • 31 Oct 2023 Trefoil Therapeutics completes a phase II OPTIC trial in Fuchs' endothelial dystrophy in USA (NCT04812067)
  • 09 May 2023 Updated efficacy data from the phase II STORM trial in Fuchs' endothelial dystrophy released by Trefoil Therapeutics

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