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Research programme: tau protein degradation-based therapeutics - Arvinas

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Drug Profile

Research programme: tau protein degradation-based therapeutics - Arvinas

Alternative Names: Brain penetrant tau PROTAC® degrader molecules; Tau-targeted PROTAC® protein degraders

Latest Information Update: 28 Aug 2023

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At a glance

  • Originator Arvinas
  • Class Antidementias; Neuroprotectants; Small molecules
  • Mechanism of Action Proteolysis; Ubiquitin protein ligase complex modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Frontotemporal dementia
  • No development reported Alzheimer's disease; Progressive supranuclear palsy

Most Recent Events

  • 28 Aug 2023 No recent reports of development identified for preclinical development in Alzheimer's-disease in USA (Parenteral, Injection)
  • 28 Aug 2023 No recent reports of development identified for preclinical development in Alzheimer's-disease in USA (PO)
  • 28 Aug 2023 No recent reports of development identified for preclinical development in Progressive-supranuclear-palsy in USA (Parenteral, Injection)

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