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PBCAR 20A

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Drug Profile

PBCAR 20A

Alternative Names: Allogeneic anti-CD20 CAR T cells - Precision BioSciences; Anti-CD20 CAR T Cells - Precision BioSciences; Anti-CD20 chimeric antigen receptor T-cell therapy - Precision BioSciences; PBCAR20A

Latest Information Update: 18 Nov 2021

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At a glance

  • Originator Precision Biosciences
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Mantle-cell lymphoma
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Chronic lymphocytic leukaemia; Non-Hodgkin's lymphoma

Most Recent Events

  • 10 Nov 2021 Discontinued - Phase-I/II for Chronic lymphocytic leukaemia (Second-line therapy or greater) in USA (IV)
  • 10 Nov 2021 Discontinued - Phase-I/II for Non-Hodgkin's lymphoma (Second-line therapy or greater) in USA (IV)
  • 12 Aug 2021 Precision BioSciences suspends phase I/II trial in Chronic lymphocytic leukaemia (Second-line therapy or greater) in USA (IV) (NCT04030195)

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