CHECKVacc
Alternative Names: CF 33 engineered with anti PD-L1 - City of Hope/Imugene; CF-33 & aPD-L1 - City of Hope/Imugene; CF33-hNIS-antiPDL1; Oncolytic Virus CF33-expressing hNIS/Anti-PD-L1 AntibodyLatest Information Update: 28 Nov 2024
At a glance
- Originator Imugene
- Class Antineoplastics; Gene therapies; Immunotherapies; Oncolytic viruses
- Mechanism of Action Cell death stimulants; Immunologic cytotoxicity; Programmed cell death-1 ligand-1 inhibitors; T lymphocyte stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- No development reported Triple negative breast cancer
Most Recent Events
- 28 Nov 2024 No recent reports of development identified for phase-I development in Triple-negative-breast-cancer(Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (Intratumoural, Injection)
- 05 Nov 2024 Imugene receives patent extension in USA
- 19 Jan 2024 Efficacy data from a phase I trial in Triple negative breast cancer released by Imugene