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TV 003

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Drug Profile

TV 003

Alternative Names: Butantan DV; Dengue Tetravalent Vaccine - Lyophilized formulation; TetraVax-DV Vaccine - Admixture TV003; TetraVax-DV-TV003; TV-003

Latest Information Update: 31 Mar 2025

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At a glance

  • Originator National Institute of Allergy and Infectious Diseases
  • Developer Butantan Institute; Medigen Vaccine Biologics; Merck & Co; National Institute of Allergy and Infectious Diseases; Panacea Biotec; Serum Institute of India
  • Class Attenuated vaccines; Dengue vaccines
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase III Dengue
  • Phase I Zika virus infection

Most Recent Events

  • 25 Mar 2025 Butantan institute plans a phase III trial for Dengue (Prevention) in Brazil (SC) (NCT06891950)
  • 12 Dec 2024 Butantan Institute in collaboration with Merck Sharp & Dohme completes a phase II trial in Dengue (Prevention, In adults) in Brazil (SC) (NCT05710224)
  • 24 Sep 2024 Phase-I clinical trials in Zika virus infection (In adults, Treatment-naive, Prevention) in USA (SC) (NCT06805487)

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