Sitneprotafib - Jacobio Pharmaceuticals
Alternative Names: JAB 3312Latest Information Update: 05 Jan 2025
At a glance
- Originator Jacobio Pharmaceuticals
- Developer AbbVie; Jacobio Pharmaceuticals
- Class Antineoplastics; Small molecules
- Mechanism of Action Protein tyrosine phosphatase non-receptor type 11 antagonists
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Orphan Drug Status
Yes - Oesophageal cancer
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase III Non-small cell lung cancer
- Phase I/II Solid tumours
Most Recent Events
- 13 Sep 2024 Efficacy data from a phase-I/II clinical trials in Solid tumours presented at the 49th European Society for Medical Oncology Congress (ESMO-2024)
- 30 Aug 2024 JAB 3312 licensed to Allist Pharmaceuticals in China, Hong Kong, Macau, and Taiwan
- 07 Aug 2024 Phase-III clinical trials in Non-small cell lung cancer (First-line therapy, Late-stage disease, Metastatic disease, Combination therapy, Inoperable/Unresectable) in China (PO) (NCT06416410)