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ONO 4685

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Drug Profile

ONO 4685

Alternative Names: ONO-4685

Latest Information Update: 28 Jun 2025

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At a glance

  • Originator Merus; Ono Pharmaceutical
  • Developer Ono Pharmaceutical
  • Class Antineoplastics; Antipsoriatics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; CD3 antigen inhibitors; Programmed cell death 1 receptor antagonists; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Chronic lymphocytic leukaemia; T-cell lymphoma
  • No development reported Autoimmune disorders; Plaque psoriasis

Most Recent Events

  • 28 Jun 2025 No recent reports of development identified for phase-I development in Autoimmune-disorders in Europe (IV, Infusion)
  • 28 Jun 2025 No recent reports of development identified for phase-I development in Autoimmune-disorders(In volunteers) in Japan (IV, Infusion)
  • 28 Jun 2025 No recent reports of development identified for phase-I development in Plaque-psoriasis(In the elderly, In adults) in Moldova (IV)

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