CB 5339
Alternative Names: CB-5339; CB-5339 tosylateLatest Information Update: 28 Aug 2024
At a glance
- Originator Cleave Therapeutics
- Developer CASI Pharmaceuticals; Cleave Therapeutics; National Cancer Institute (USA)
- Class Antineoplastics; Small molecules
- Mechanism of Action CDC48 inhibitors; P97 ATPase inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Preclinical Multiple myeloma
- No development reported Acute myeloid leukaemia; Myelodysplastic syndromes; Solid tumours
- Discontinued Lymphoma
Most Recent Events
- 28 Aug 2024 No recent reports of development identified for phase-I development in Acute-myeloid-leukaemia(Second-line therapy or greater) in Australia (PO, Capsule)
- 28 Aug 2024 No recent reports of development identified for phase-I development in Acute-myeloid-leukaemia(Second-line therapy or greater) in USA (PO, Capsule)
- 28 Aug 2024 No recent reports of development identified for phase-I development in Myelodysplastic-syndromes(Second-line therapy or greater) in Australia (PO, Capsule)