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Atamparib - Nerviano Medical Sciences

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Drug Profile

Atamparib - Nerviano Medical Sciences

Alternative Names: ONO-7119; RBN-2397

Latest Information Update: 04 Feb 2026

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At a glance

  • Originator Ribon Therapeutics
  • Developer Ono Pharmaceutical; Ribon Therapeutics
  • Class Amines; Antineoplastics; Ethers; Fluorinated hydrocarbons; Ketones; Piperazines; Pyridazines; Pyrimidines; Small molecules
  • Mechanism of Action Poly(ADP-ribose) polymerase 7 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Squamous cell cancer
  • No development reported Solid tumours

Most Recent Events

  • 04 Feb 2026 Discontinued - Phase-I for Solid tumours (Combination therapy) in Japan (PO)
  • 28 Jan 2026 Nerviano Medical Sciences plans phase I/II trial for Solid tumours and Adenocarcinoma (Late-stage disease, Metastatic disease) in China (PO) in February 2026 (NCT07374419)
  • 12 Jan 2026 The China’s NMPA approves IND application for atamparib in advanced solid tumors

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