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Atamparib - Ribon Therapeutics

Drug Profile

Atamparib - Ribon Therapeutics

Alternative Names: ONO-7119; RBN-2397

Latest Information Update: 27 Apr 2023

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At a glance

  • Originator Ribon Therapeutics
  • Developer Ono Pharmaceutical; Ribon Therapeutics
  • Class Amines; Antineoplastics; Ethers; Fluorinated hydrocarbons; Ketones; Piperazines; Pyridazines; Pyrimidines; Small molecules
  • Mechanism of Action Poly(ADP-ribose) polymerase 7 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Squamous cell cancer
  • Phase I Solid tumours

Most Recent Events

  • 27 Apr 2023 3776005 - updated intro, KDM, added DEV lines, added TT data, minor updates in AE and PD data, added HE
  • 14 Apr 2023 Efficacy and adverse events data from a phase I/II trial in Squamous cell cancer presented at the 114th Annual Meeting of the American Association for Cancer Research (AACR-2023)
  • 14 Apr 2023 Pharmacodynamics data from a preclinical trial in solid-tumours presented at the 114th Annual Meeting of the American Association for Cancer Research (AACR-2023)
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