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Ifenprodil - Algernon Pharmaceuticals

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Drug Profile

Ifenprodil - Algernon Pharmaceuticals

Alternative Names: NP 120

Latest Information Update: 29 Mar 2024

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At a glance

  • Originator Algernon Pharmaceuticals
  • Developer Algernon Pharmaceuticals; Dartmouth College
  • Class Anti-inflammatories; Antifibrotics; Antineoplastics; Antipsychotics; Antitussives; Antivirals; Benzyl compounds; Peripheral vasodilators; Phenols; Piperidines; Small molecules; Vascular disorder therapies
  • Mechanism of Action Alpha adrenergic receptor antagonists; NMDA receptor antagonists; Sigma-1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Idiopathic pulmonary fibrosis
  • New Molecular Entity No

Highest Development Phases

  • Phase II Cough; Idiopathic pulmonary fibrosis
  • Preclinical Acute lung injury; Influenza A virus H5N1 subtype; Neuroendocrine tumours; Pancreatic cancer; Small cell lung cancer
  • Research Respiration disorders
  • No development reported Crohn's disease; Ulcerative colitis
  • Discontinued COVID 2019 infections

Most Recent Events

  • 27 Mar 2024 Seyltx acquires ifenprodil from Algernon Pharmaceuticals
  • 27 Mar 2024 Seyltx plans a phase IIb trial for Cough in 2024
  • 26 Mar 2024 Assistance Publique Hopitaux de Paris plans a phase II trial for Multiple sclerosis in France, in March 2024 (NCT06330077)
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