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Pimicotinib - Abbisko Therapeutics

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Drug Profile

Pimicotinib - Abbisko Therapeutics

Alternative Names: ABSK-021

Latest Information Update: 24 Oct 2025

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At a glance

  • Originator Abbisko Therapeutics
  • Developer Abbisko Therapeutics; Sperogenix Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Macrophage colony-stimulating factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Giant cell tumours
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preregistration Giant cell tumour of tendon sheath
  • Phase III Solid tumours
  • Phase II Graft-versus-host disease; Pancreatic cancer
  • Preclinical Osteosarcoma
  • No development reported Amyotrophic lateral sclerosis

Most Recent Events

  • 17 Oct 2025 Efficacy and adverse events data from a phase III MANEUVER trial in Giant cell tumour of tendon sheath released by Merck .
  • 12 Sep 2025 Abbisko Therapeutics initiates enrollment in a phase-I pharmacokinetics trial (In volunteers) in China (PO) (NCT07210996)
  • 28 Aug 2025 No recent reports of development identified for preclinical development in Amyotrophic-lateral-sclerosis in China (PO)

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