Pimicotinib - Abbisko Therapeutics
Alternative Names: ABSK-021Latest Information Update: 28 Oct 2026
At a glance
- Originator Abbisko Therapeutics
- Developer Abbisko Therapeutics; Merck AG; Sperogenix Therapeutics
- Class Amides; Antineoplastics; Ethers; Pyrazoles; Pyridines; Pyrrolidinones; Small molecules
- Mechanism of Action Macrophage colony-stimulating factor receptor antagonists
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Orphan Drug Status
Yes - Giant cell tumours
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Registered Giant cell tumour of tendon sheath
- Phase III Solid tumours
- Phase II Graft-versus-host disease; Pancreatic cancer
- No development reported Amyotrophic lateral sclerosis
Most Recent Events
- 26 Oct 2026 Efficacy and safety data from a phase III MANEUVER trial in Giant cell tumour of tendon sheath released by Merck KGaA
- 30 Jun 2026 Registered for Giant cell tumour of tendon sheath (Late-stage disease, Inoperable/Unresectable) in Canada (PO)
- 16 Jun 2026 Abbisko Therapeutics plans a phase II NEXPERT trial for Giant cell tumour of tendon sheath(Neoadjuvant therapy) in China (PO) (NCT07707882)