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App2 M1

Drug Profile

App2 M1

Alternative Names: Aap2-M1; App2‐M1

Latest Information Update: 25 Apr 2024

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At a glance

  • Originator ContraFect
  • Class Antibacterials; Peptide antibiotics
  • Mechanism of Action Cell wall inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Gram-negative infections

Most Recent Events

  • 04 Dec 2023 Discontinued - Preclinical for Gram-negative infections in USA (Parenteral) as ContraFect filed for voluntary bankruptcy under chapter 11 of the US Bankruptcy code
  • 28 Sep 2023 No recent reports of development identified for preclinical development in Gram-negative-infections in USA (Parenteral)
  • 03 Sep 2019 Pharmacodynamics data from an ex-vivo study in Gram-negative infections presented at the American Society of Microbiology and European Society of Clinical Microbiology and Infectious Disease (ASM-ESCMID-2019)

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