App2 M1
Alternative Names: Aap2-M1; App2‐M1Latest Information Update: 25 Apr 2024
At a glance
- Originator ContraFect
- Class Antibacterials; Peptide antibiotics
- Mechanism of Action Cell wall inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Discontinued Gram-negative infections
Most Recent Events
- 04 Dec 2023 Discontinued - Preclinical for Gram-negative infections in USA (Parenteral) as ContraFect filed for voluntary bankruptcy under chapter 11 of the US Bankruptcy code
- 28 Sep 2023 No recent reports of development identified for preclinical development in Gram-negative-infections in USA (Parenteral)
- 03 Sep 2019 Pharmacodynamics data from an ex-vivo study in Gram-negative infections presented at the American Society of Microbiology and European Society of Clinical Microbiology and Infectious Disease (ASM-ESCMID-2019)