Camonsertib - Repare Therapeutics
Alternative Names: RG-6526; RP-3500Latest Information Update: 23 Sep 2025
At a glance
- Originator Repare Therapeutics
- Class Antineoplastics; Morpholines; Pyrazoles; Pyridines; Small molecules
- Mechanism of Action ATR protein inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
- Available For Licensing Yes - Cancer
Highest Development Phases
- Phase II Solid tumours
- Phase I/II Chronic lymphocytic leukaemia; Non-small cell lung cancer
Most Recent Events
- 05 Sep 2025 Repare Therapeutics in collaboration with National Cancer Institute plans a phase I trial for Head and neck cancer (Combination therapy, Inoperable, Recurrent) (PO) in December 2025 (NCT07156227)
- 25 Apr 2025 Efficacy, pharmacodynamics and adverse events data from the MYTHIC phase I trial in Solid tumours presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
- 25 Apr 2025 Pharmacodynamics data from a preclinical trial in Breast cancer presented at the 116th Annual Meeting of the American Association for Cancer Research 2025 (AACR-2025)