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Camonsertib - Repare Therapeutics

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Drug Profile

Camonsertib - Repare Therapeutics

Alternative Names: RG-6526; RP-3500

Latest Information Update: 02 Jul 2024

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At a glance

  • Originator Repare Therapeutics
  • Class Antineoplastics; Morpholines; Pyrazoles; Pyridines; Small molecules
  • Mechanism of Action ATR protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Cancer

Highest Development Phases

  • Phase II Solid tumours
  • Phase I/II Chronic lymphocytic leukaemia; Non-small cell lung cancer

Most Recent Events

  • 31 May 2024 Efficacy and adverse event data from the phase II TAPISTRY trial in Solid tumors presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)
  • 07 May 2024 Roche terminates the worldwide license and collaboration agreement with Repare Therapeutics for the development and commercialisation of camonsertib for solid tumours
  • 13 Feb 2024 Repare Therapeutics re-initiates enrolment in the phase I/II CORONADO CLL trial in Chronic lymphocytic leukaemia (Combination therapy, Second-line therapy or greater) in USA (PO) (NCT05405309)

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