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NKX 101

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Drug Profile

NKX 101

Alternative Names: CAR NKG2D NK cells; NKG2D; NKX-101

Latest Information Update: 14 Jun 2024

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At a glance

  • Originator Nkarta Therapeutics
  • Class Antineoplastics; CAR-NK cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; Natural killer cell replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia
  • New Molecular Entity No

Highest Development Phases

  • Suspended Acute myeloid leukaemia; Cholangiocarcinoma; Colorectal cancer; Liver cancer; Myelodysplastic syndromes; Osteosarcoma

Most Recent Events

  • 05 Jun 2024 Pharmacodynamics data from two preclinical trials in Acute myeloid leukaemia presented at the 115th Annual Meeting of the American Association for Cancer Research (AACR-2024)
  • 21 Mar 2024 Suspended - Phase-I for Acute myeloid leukaemia (Second-line therapy or greater) in USA (IV)
  • 21 Mar 2024 Suspended - Phase-I for Myelodysplastic syndromes in USA (IV)

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