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Aprepitant - George Washington University/Hoth Therapeutics

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Drug Profile

Aprepitant - George Washington University/Hoth Therapeutics

Alternative Names: HT-001; WEG-232

Latest Information Update: 17 Sep 2025

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At a glance

  • Originator The George Washington University
  • Developer Hoth Therapeutics; The George Washington University
  • Class Anti-inflammatories; Antidepressants; Antiemetics; Antineoplastics; Antitussives; Antivirals; Fluorobenzenes; Ketones; Morpholines; Skin disorder therapies; Small molecules; Triazoles
  • Mechanism of Action Neurokinin 1 receptor antagonists; Virus replication inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Skin disorders

Most Recent Events

  • 10 Sep 2025 Hoth Therapeutics submits CTA to EMA to expand phase II trial in Skin disorders
  • 10 Sep 2025 Hoth Therapeutics expects to initiate european patient recruitment in early 2026
  • 29 Jul 2025 Hoth Therapeutics expects Clinical Trial Application approval for a phase II trial in Skin disorders (Chemotherapy-induced) from EMA in 2025

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