Drug Profile

EXN 407

Alternative Names: EXN-407

Latest Information Update: 04 Aug 2025

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At a glance

Originator Exonate
Class Eye disorder therapies; Small molecules
Mechanism of Action Cyclin-dependent kinase-activating kinase inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I/II Diabetic macular oedema
No development reported Wet age-related macular degeneration

Most Recent Events

29 Jul 2025 Adverse events data from a phase Ib/IIa trial in Diabetic macular oedema released by Exonate
29 Jul 2025 Exonate plans the phase IIb CLEAR-DE trial for Diabetic retinopathy in Australia, Middle East and China (Opthalmic) in first quarter 2025
12 Mar 2024 Exonate collaborates with Exploristics for a phase IIb trial in Diabetic macular oedema

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