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VNLG 152

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Drug Profile

VNLG 152

Alternative Names: HT 003D; HT 003IBD; HT-003; VNLG -152

Latest Information Update: 13 Aug 2025

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At a glance

  • Originator Isoprene Pharmaceuticals; University of Maryland, Baltimore
  • Developer Hoth Therapeutics; University of Maryland, Baltimore; Weill Cornell Medicine
  • Class Anti-inflammatories; Antineoplastics; Skin disorder therapies
  • Mechanism of Action Retinoic acid metabolism inhibitors; Toll-like receptor 2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Acne; Psoriasis
  • Research Inflammatory bowel diseases
  • No development reported Cancer

Most Recent Events

  • 16 Apr 2024 VNLG 152 is still in preclinical development for Acne in USA
  • 28 Feb 2024 No recent reports of development identified for preclinical development in Cancer in USA (PO)
  • 21 Oct 2021 Preclinical trials in Psoriasis in USA (unspecified route) (Hoth Therapeutics pipeline, October 2021)

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