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AZD 0120

X
Drug Profile

AZD 0120

Alternative Names: AZD-0120; BCMA-Antigen X Bispecific CAR-Modified T Cells-Gracell-Biotechnology; BCMA-Antigen X bispecific CAR-T cells; BCMA/CD19 dual-target CAR-T cell immunotherapy - Gracell Biotechnology; BCMA/CD19 dual-targeting CAR-T therapy; CD19-BCMA CAR-T cells; Dual CAR-BCMA-19; FasTCAR-T GC012F; GC 012; GC-012F

Latest Information Update: 20 Jan 2025

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At a glance

  • Originator Gracell Biotechnology
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies; T lymphocyte cell therapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Multiple myeloma
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Multiple myeloma; Systemic lupus erythematosus
  • Phase 0 Myasthenia gravis
  • No development reported Non-Hodgkin's lymphoma

Most Recent Events

  • 06 Jan 2025 Gracell Biotechnologies plans a phase I trial for Myasthenia Gravis (Treatment-experienced) in China (IV) in February 2025 (NCT06759948)
  • 25 Aug 2024 Phase-I/II clinical trials in Systemic lupus erythematosus (Treatment-experienced) in China (IV) (NCT06530849)
  • 28 Jul 2024 No recent reports of development identified for phase-I development in Non-Hodgkin's-lymphoma(Second-line therapy or greater) in China

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