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AK OTOF

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Drug Profile

AK OTOF

Alternative Names: AAVAnc80-hOTOF; AAVAnc80-hOTOF Vector; AK-OTOF; OTOF Gene Therapy - Eli Lilly and Company

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Akouos
  • Class Gene therapies
  • Mechanism of Action Gene transference; OTOF protein replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Sensorineural hearing loss
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Sensorineural hearing loss

Most Recent Events

  • 20 Apr 2023 Phase-I/II clinical trials in Sensorineural hearing loss (In adolescents, In adults, In children, In the elderly) in USA (Otic) (NCT05821959)
  • 01 Dec 2022 Akouos has been acquired by Eli Lilly and Company
  • 13 Sep 2022 Akouos plans a phase I/II trial for the treatment of OTOF-mediated hearing loss (In Children) in the US and other countries (9368521; 9374322)

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