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IMGN 151

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Drug Profile

IMGN 151

Alternative Names: IMGN-151

Latest Information Update: 28 Jun 2025

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At a glance

  • Originator ImmunoGen
  • Class Antineoplastics; Bispecific antibodies; Drug conjugates; Immunoconjugates; Maytansinoids
  • Mechanism of Action Apoptosis stimulants; Mitosis inhibitors; Tubulin inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Phase I Endometrial cancer
  • No development reported Breast cancer; Cervical cancer; Non-small cell lung cancer

Most Recent Events

  • 28 Jun 2025 No recent reports of development identified for preclinical development in Non-small-cell-lung-cancer in USA (Parenteral)
  • 24 Jun 2025 Phase-I/II clinical trials in Fallopian tube cancer (Second-line therapy or greater, Combination therapy) in Belgium, Germany, Italy, Spain, Netherlands (IV) (NCT07024784) (EudraCT2023-506842-22-00)
  • 24 Jun 2025 Phase-I/II clinical trials in Fallopian tube cancer (Second-line therapy or greater, Monotherapy) in Belgium, Germany, Italy, Spain, Netherlands (IV) (NCT07024784) (EudraCT2023-506842-22-00)

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