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ADG 116

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Drug Profile

ADG 116

Alternative Names: ADG-116

Latest Information Update: 28 Jan 2026

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At a glance

  • Originator Adagene
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Cytotoxic T-lymphocyte antigen 4 inhibitors; Regulatory T-lymphocyte inhibitors; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 30 Nov 2025 Adagene completes a phase-I/II trial in Solid tumours (Combination therapy, Late-stage disease, Monotherapy, Metastatic disease, Second-line therapy or greater) in Australia and USA (IV) (NCT04501276)
  • 28 Apr 2025 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease, Metastatic disease, Monotherapy) in China (IV)
  • 31 Aug 2023 Efficacy and adverse events data from phase Ib/II trial in Solid tumours released by Adagene

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