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AL 101 - Alector/Adimab

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Drug Profile

AL 101 - Alector/Adimab

Alternative Names: AL101 - Alector; GSK-4527226

Latest Information Update: 18 Aug 2025

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At a glance

  • Originator Adimab; Alector
  • Developer Alector; GSK
  • Class Antidementias; Antiparkinsonians; Monoclonal antibodies
  • Mechanism of Action Sortilin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Alzheimer's disease
  • No development reported Dementia; Parkinson's disease

Most Recent Events

  • 11 Aug 2025 GlaxoSmithKline plans a phase II trial for Alzheimer's disease (Treatment experienced) in August 2025 (EudraCT 2025-521107-42) (NCT07105709)
  • 28 Feb 2025 No recent reports of development identified for phase-I development in Alzheimer's-disease(In volunteers) in USA (SC)
  • 28 Feb 2025 No recent reports of development identified for phase-I development in Dementia(In volunteers) in USA (IV)

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