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Opakalim - Biohaven Pharmaceuticals

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Drug Profile

Opakalim - Biohaven Pharmaceuticals

Alternative Names: BHV-7000; BPN-25203; KB-3061

Latest Information Update: 23 Jan 2026

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At a glance

  • Originator Channel Biosciences
  • Developer Biohaven Pharmaceuticals; Biohaven Therapeutics
  • Class Alkanes; Amides; Analgesics; Antidepressants; Antiepileptic drugs; Benzimidazoles; Fluorobenzenes; Mood stabilisers; Neuropsychotherapeutics; Nitriles; Small molecules
  • Mechanism of Action KCNQ2 potassium channel stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Bipolar disorders; Epilepsy; Partial epilepsies
  • Phase II Major depressive disorder
  • Phase I Erythromelalgia; Pain
  • No development reported Infantile spasms; Mood disorders

Most Recent Events

  • 23 Jan 2026 Chemical structure information added.
  • 15 Jan 2026 Phase-I clinical trials in Erythromelalgia in USA (PO) (NCT07262268)
  • 28 Nov 2025 No recent reports of development identified for phase-I development in Infantile spasms(In neonates) in USA (PO)

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