PH 762
Alternative Names: PH 762 adoptive cell therapy; PH-762; PH762-ACT; RXI 762-ACTLatest Information Update: 29 Apr 2025
At a glance
- Originator Phio Pharmaceuticals
- Developer AgonOx; Phio Pharmaceuticals
- Class Antineoplastics; Gene therapies; Immunotherapies; Small interfering RNA; T lymphocyte cell therapies
- Mechanism of Action Programmed cell death 1 receptor expression inhibitors; RNA interference
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Phase I Malignant melanoma; Merkel cell carcinoma; Solid tumours; Squamous cell cancer
Most Recent Events
- 31 Dec 2024 Phio Pharmaceuticals has patent protection for INTASYL™technology
- 31 May 2024 Phio Pharmaceuticals terminates Clinical Co-Development Agreement with AgonOx for clinical development of PH 762
- 05 Apr 2024 Interim efficacy and adverse events data from a phase I trial in solid tumours presented at the 115th Annual Meeting of the American Association for Cancer Research (AACR-2024)