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PH 762

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Drug Profile

PH 762

Alternative Names: PH 762 adoptive cell therapy; PH-762; PH762-ACT; RXI 762-ACT

Latest Information Update: 27 Aug 2025

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At a glance

  • Originator Phio Pharmaceuticals
  • Developer AgonOx; Phio Pharmaceuticals
  • Class Antineoplastics; Gene therapies; Immunotherapies; Small interfering RNA; T lymphocyte cell therapies
  • Mechanism of Action Programmed cell death 1 receptor expression inhibitors; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I Malignant melanoma; Merkel cell carcinoma; Solid tumours; Squamous cell cancer

Most Recent Events

  • 30 May 2025 Efficacy and adverse events data from a phase I trial in squamous cell cancer, malignant melanoma presented at the 61st Annual Meeting of the American Society of Clinical Oncology (ASCO-2025)
  • 31 Dec 2024 Phio Pharmaceuticals has patent protection for INTASYL™technology
  • 31 May 2024 Phio Pharmaceuticals terminates Clinical Co-Development Agreement with AgonOx for clinical development of PH 762

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