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ARO ENaC

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Drug Profile

ARO ENaC

Alternative Names: ARO-ENaC; ARO-Lung1

Latest Information Update: 01 Mar 2022

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At a glance

  • Originator Arrowhead Pharmaceuticals
  • Class Antifibrotics; Small interfering RNA
  • Mechanism of Action RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Cystic fibrosis

Most Recent Events

  • 08 Feb 2022 Arrowhead Pharmaceuticals terminates the phase I/II AROENaC1001 trial for Cystic fibrosis in Australia and New Zealand due to business decisions (NCT04375514)
  • 02 Jul 2021 Arrowhead Pharmaceuticals temporarily pauses Phase-I/II clinical trials in Cystic fibrosis in Australia and New Zealand pending toxicology analysis (Inhalation) (NCT04375514)
  • 24 Feb 2021 Phase-I/II clinical trials in Cystic fibrosis in Australia (Inhalation) before February 2021 (NCT04375514)

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