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MuSK CAART

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Drug Profile

MuSK CAART

Alternative Names: Muscle Specific Kinase chimeric autoantibody receptor T cells - Cabaletta Bio; MuSK Chimeric Autoantibody Receptor (CAAR) T Cells; MuSK-CAART

Latest Information Update: 09 Dec 2022

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At a glance

  • Originator University of Pennsylvania
  • Developer Cabaletta Bio
  • Class Gene therapies; T lymphocyte cell therapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Myasthenia gravis
  • New Molecular Entity No

Highest Development Phases

  • Phase I Myasthenia gravis

Most Recent Events

  • 01 Dec 2022 Phase-I clinical trials in Myasthenia gravis in USA (Parenteral) (NCT05451212)
  • 31 Oct 2022 MuSK CAART receives Orphan Drug status for Myasthenia gravis in USA
  • 30 Jun 2022 Cabaletta Bio files an NOC application with the Health Canada in Canda for Myasthenia gravis before June 2022

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