BNT 211
Alternative Names: Anti-claudin 6 CAR T-cell therapy - BioNTech; Anti-claudin 6 chimeric antigen receptor cell therapy - BioNTech; Anti-CLDN6 chimeric antigen receptor cell therapy - BioNTech; BNT-211; CLDN6 CAR-T therapy - BioNTechLatest Information Update: 05 May 2025
At a glance
- Originator BioNTech
- Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
- Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Phase I/II Solid tumours
Most Recent Events
- 23 Apr 2025 BioNTech SE plans a phase II trial for Germ cell cancer (Second-line therapy or greater) in July 2025 (IV, Infusion) (NCT06940804)
- 10 Mar 2025 BNT 211 receives Regenerative Medicine Advanced Therapy (RMAT) status for Solid tumours in USA
- 13 Sep 2024 Efficacy and adverse events data from phase I/II clinical trials in Solid tumours presented at the 49th European Society for Medical Oncology Congress (ESMO-2024)