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BNT 211

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Drug Profile

BNT 211

Alternative Names: Anti-claudin 6 CAR T-cell therapy - BioNTech; Anti-claudin 6 chimeric antigen receptor cell therapy - BioNTech; Anti-CLDN6 chimeric antigen receptor cell therapy - BioNTech; BNT-211; CLDN6 CAR-T therapy - BioNTech

Latest Information Update: 19 Mar 2025

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At a glance

  • Originator BioNTech
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 10 Mar 2025 BNT 211 receives Regenerative Medicine Advanced Therapy (RMAT) status for Solid tumours in USA
  • 13 Sep 2024 Efficacy and adverse events data from phase I/II clinical trials in Solid tumours presented at the 49th European Society for Medical Oncology Congress (ESMO-2024)
  • 09 Jan 2024 BioNTech plans a pivotal phase II trial in Germ cell cancer (Second-line therapy or greater) (IV, Infusion), in 2024

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