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Research programme: HDAC6-Pi3K-delta dual inhibitors - Tharimmune/National Center for Advancing Translational Sciences

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Drug Profile

Research programme: HDAC6-Pi3K-delta dual inhibitors - Tharimmune/National Center for Advancing Translational Sciences

Alternative Names: HSB-510

Latest Information Update: 15 Jan 2024

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At a glance

  • Originator Hillstream BioPharma; National Center for Advancing Translational Sciences
  • Developer National Center for Advancing Translational Sciences; Tharimmune
  • Class Antineoplastics; Small molecules
  • Mechanism of Action HDAC6 protein inhibitors; Phosphatidylinositol 3 kinase delta inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Acute myeloid leukaemia; Precursor B-cell lymphoblastic leukaemia-lymphoma; Solid tumours

Most Recent Events

  • 14 Apr 2023 Pharmacodynamics data from preclinical studies in Solid tumours presented at the 114th Annual Meeting of the American Association for Cancer Research (AACR-2023)
  • 15 Feb 2023 Preclinical trials in Acute myeloid leukaemia in USA (unspecified route) prior to February 2023
  • 15 Feb 2023 Preclinical trials in Precursor B-cell lymphoblastic leukaemia-lymphoma in USA (unspecified route) prior to February 2023

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