SON 1010
Alternative Names: IL12-FHAB; SON-1010Latest Information Update: 19 Feb 2026
At a glance
- Originator Sonnet Biotherapeutics
- Developer Sonnet BioTherapeutics Holdings, Inc
- Class Antineoplastics; Immunoglobulin fragments; Immunoglobulin Fv fragments; Immunotherapies; Interleukins; Recombinant fusion proteins
- Mechanism of Action Interleukin 12 replacements
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
- Available For Licensing Yes
Highest Development Phases
- Phase I/II Ovarian cancer; Solid tumours
Most Recent Events
- 03 Feb 2026 Sonnet BioTherapeutics terminates a phase-I/II clinical trials in Solid tumours (Metastatic disease, Late-stage disease, Second-line therapy or greater, Combination therapy) in Australia and USA (SC) because trial failed to meet efficacy endpoint despite lack of safety concern (NCT05756907)
- 15 Oct 2025 Sonnet BioTherapeutics collaborates with Spanios for SON-1010 for Cancer
- 28 May 2025 No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy, Late-stage disease, Metastatic disease) in USA (SC)