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SON 1010

Drug Profile

SON 1010

Alternative Names: IL12-FHAB; SON-1010

Latest Information Update: 19 Feb 2026

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At a glance

  • Originator Sonnet Biotherapeutics
  • Developer Sonnet BioTherapeutics Holdings, Inc
  • Class Antineoplastics; Immunoglobulin fragments; Immunoglobulin Fv fragments; Immunotherapies; Interleukins; Recombinant fusion proteins
  • Mechanism of Action Interleukin 12 replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I/II Ovarian cancer; Solid tumours

Most Recent Events

  • 03 Feb 2026 Sonnet BioTherapeutics terminates a phase-I/II clinical trials in Solid tumours (Metastatic disease, Late-stage disease, Second-line therapy or greater, Combination therapy) in Australia and USA (SC) because trial failed to meet efficacy endpoint despite lack of safety concern (NCT05756907)
  • 15 Oct 2025 Sonnet BioTherapeutics collaborates with Spanios for SON-1010 for Cancer
  • 28 May 2025 No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy, Late-stage disease, Metastatic disease) in USA (SC)

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