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AFM 24

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Drug Profile

AFM 24

Alternative Names: AFM-24; EGFR/CD16A ICE®

Latest Information Update: 17 Jul 2026

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At a glance

  • Originator Affimed Therapeutics
  • Developer Affimed Therapeutics; NKGen Biotech
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Natural killer cell stimulants; Phagocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 14 Jul 2026 XOMA has been acquired by Ligand Pharmaceuticals
  • 06 Sep 2025 Updated efficacy and adverse events data from the phase I/II AFM24-102 trial in Solid tumours presented at the 26th World Conference on Lung Cancer (WCLC-2025)
  • 30 May 2025 Updated efficacy and adverse events data from the phase I/II AFM24-102 trial in Solid tumours presented at the 61st Annual Meeting of the American Society of Clinical Oncology (ASCO-2025)

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