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SY 5609

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Drug Profile

SY 5609

Alternative Names: Oral CDK7 inhibitor - Syros Pharmaceuticals; SY-5609

Latest Information Update: 28 Apr 2025

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At a glance

  • Originator Syros Pharmaceuticals
  • Developer Roche; Syros Pharmaceuticals
  • Class Amines; Antineoplastics; Fluorinated hydrocarbons; Indoles; Nitriles; Phosphorus compounds; Piperidines; Small molecules
  • Mechanism of Action Cyclin-dependent kinase-activating kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pancreatic cancer
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • No development reported Breast cancer; Colorectal cancer; Pancreatic cancer; Small cell lung cancer; Solid tumours
  • Discontinued Haematological malignancies

Most Recent Events

  • 28 Apr 2025 No recent reports of development identified for phase-I development in Breast-cancer(Combination therapy, Metastatic disease, Second-line therapy or greater, Treatment-resistant) in USA (PO)
  • 28 Apr 2025 No recent reports of development identified for phase-I development in Breast-cancer(Late-stage disease, Monotherapy, Second-line therapy or greater) in USA (PO)
  • 28 Apr 2025 No recent reports of development identified for phase-I development in Colorectal-cancer(Combination therapy, Metastatic disease, Second-line therapy or greater) in Australia (PO)

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