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AVA 6000

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Drug Profile

AVA 6000

Alternative Names: AVA-6000; AVA6000 pro-Doxorubicin; FAP Pro-doxorubicin

Latest Information Update: 06 Jun 2025

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At a glance

  • Originator Tufts University School of Medicine
  • Developer Avacta
  • Class Anthracyclines; Antineoplastics; Cytostatic antibiotics; Doxorubicins; Peptide drug conjugates; Small molecules
  • Mechanism of Action DNA intercalators; Type II DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Soft tissue sarcoma
  • New Molecular Entity No

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 25 Apr 2025 Pharmacokinetics data from a phase I trial in Solid tumours presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 25 Apr 2025 Pharmacokinetics data from a preclinical study in Solid tumours presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 07 Mar 2025 Efficacy data from a phase I trial in Solid tumors released by Avacta

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