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Emraclidine - Cerevel Therapeutics

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Drug Profile

Emraclidine - Cerevel Therapeutics

Alternative Names: CVL-231; PF-06852231

Latest Information Update: 28 Jan 2026

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At a glance

  • Originator Pfizer
  • Developer Cerevel Therapeutics; Pfizer
  • Class Antidementias; Antipsychotics; Azetidines; Fluorobenzenes; Ketones; Pyridines; Pyrroles; Small molecules
  • Mechanism of Action Muscarinic M4 receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Schizophrenia
  • No development reported Alzheimer's disease

Most Recent Events

  • 28 Jan 2026 No recent reports of development identified for phase-I development in Alzheimer's-disease(In the elderly, In volunteers) in USA (PO, Tablet)
  • 08 Oct 2025 AbbVie initiates a phase I pharmacokinetics trial in Healthy elderly volunteers in USA (PO, Tablet) (NCT07219030)
  • 04 Aug 2025 AbbVie initiates enrolment in a phase II trial for Schizophrenia in USA (NCT07145918)

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