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Emraclidine - Cerevel Therapeutics

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Drug Profile

Emraclidine - Cerevel Therapeutics

Alternative Names: CVL-231; PF-06852231

Latest Information Update: 07 Sep 2025

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At a glance

  • Originator Pfizer
  • Developer Cerevel Therapeutics; Pfizer
  • Class Antidementias; Antipsychotics; Azetidines; Fluorobenzenes; Ketones; Pyridines; Pyrroles; Small molecules
  • Mechanism of Action Muscarinic M4 receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Schizophrenia
  • Phase I Alzheimer's disease

Most Recent Events

  • 04 Aug 2025 AbbVie initiates enrolment in a phase II trial for Schizophrenia in USA (NCT07145918)
  • 25 Jun 2025 Cerevel Therapeutics completes the phase II EMPOWER-3 trial in Schizophrenia in USA, Bulgaria, Hungary, Peurto Rico, Ukriane (PO) (NCT05443724) (EudraCT2022-001151-16)
  • 14 Apr 2025 Cerevel Therapeutics completes a phase I trial in Alzheimer's disease (In volunteers, In the elderly) in USA (PO) (NCT05644977)

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