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Adimanebart - argenx

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Drug Profile

Adimanebart - argenx

Alternative Names: ARGX-119

Latest Information Update: 22 Jan 2026

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At a glance

  • Originator argenx; Leiden University Medical Center
  • Developer argenx
  • Class Antibodies; Monoclonal antibodies
  • Mechanism of Action MUSK protein agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Amyotrophic lateral sclerosis; Spinal muscular atrophy
  • Phase I Congenital myasthenic syndromes

Most Recent Events

  • 12 Jan 2026 Argenx plans a phase III registrational trial for Congenital myasthenic syndromes (IV) in the third quarter of 2026
  • 19 Dec 2025 Phase-II clinical trials in Spinal muscular atrophy (In children, In adolescents, Treatment-experienced) in USA (IV, infusion) (NCT07287982)
  • 19 Dec 2025 Argenx plans a phase II trial for Spinal muscular atrophy (In Children, In adolescents) (IV, Infusion) in December 2025 (NCT07287982)

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