CTX 8371
Alternative Names: CTX-8371; CTX-8371/PD-1 x PD-L1; PD-1 x PD-L1Latest Information Update: 02 Apr 2024
At a glance
- Originator Compass Therapeutics
- Class Antineoplastics; Bispecific antibodies; Immunotherapies
- Mechanism of Action Antibody-dependent cell cytotoxicity; Programmed cell death 1 receptor antagonists; Programmed cell death-1 ligand-1 inhibitors; T lymphocyte stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
- Available For Licensing Yes
Highest Development Phases
- Phase I Hodgkin's disease; Solid tumours
Most Recent Events
- 19 Mar 2024 Phase-I clinical trials in Hodgkin's disease (Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV) (NCT06150664)
- 19 Mar 2024 Phase-I clinical trials in Solid tumours (Late-stage disease, Metastatic disease, Inoperable/Unresectable, Second-line therapy or greater) in USA (IV) (NCT06150664)
- 28 Feb 2024 Pharmacodynamics data from a preclinical studies in Solid tumors released by Compass Therapeutics