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Lotiglipron - Pfizer

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Drug Profile

Lotiglipron - Pfizer

Alternative Names: PF-07081532

Latest Information Update: 02 Apr 2024

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At a glance

  • Originator Sosei Heptares
  • Developer Pfizer
  • Class Antihyperglycaemics; Obesity therapies; Small molecules
  • Mechanism of Action Glucagon-like peptide-1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Obesity; Type 2 diabetes mellitus

Most Recent Events

  • 31 Mar 2024 Sosei Heptares is now called Nxera Pharma
  • 26 Dec 2023 Pfizer terminates a phase-I trial in Obesity in USA based on pharmacokinetic data from phase I drug-drug interaction studies (NCT05671653)
  • 20 Jul 2023 Pfizer completes a phase I trial in Type 2 diabetes mellitus in USA (NCT05510245)

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