BNT 141
Alternative Names: BNT-141Latest Information Update: 12 Oct 2023
At a glance
- Originator BioNTech
- Class Antibodies; Antineoplastics; Immunotherapies; RNA
- Mechanism of Action Claudin 18 protein inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I/II Solid tumours
Most Recent Events
- 29 Sep 2023 BioNTech SE terminates a phase I/II trial in Solid tumours (Combination therapy, Metastatic disease, Second-line therapy or greater) in Canada, Denmark, Netherlands, Spain, USA (IV, Injection), due to sponsor decision (NCT04683939)
- 08 Nov 2021 Phase-I/II clinical trials in Solid tumours (Metastatic disease, Monotherapy, Second-line therapy or greater) in USA (IV) as of November 2021 (NCT04683939)
- 08 Nov 2021 Phase-I/II clinical trials in Solid tumours (Metastatic disease, Second-line therapy or greater, Combination therapy) in USA (IV) as of November 2021 (NCT04683939)