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BI 1387446 - Boehringer-Ingelheim

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Drug Profile

BI 1387446 - Boehringer-Ingelheim

Alternative Names: BI-1387446

Latest Information Update: 19 Apr 2024

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At a glance

  • Originator Boehringer Ingelheim
  • Class Antineoplastics; Small molecules
  • Mechanism of Action STING1 protein stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 19 Mar 2024 Boehringer Ingelheim completes phase I trial in Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Monotherapy, Combination therapy, Second-line therapy or greater) in United Kingdom, USA and Spain (Intratumoural) (NCT04147234)
  • 20 Oct 2023 BI 1387446 is still in phase I trials for Solid tumours(Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in Spain (Intratumoural, Injection)
  • 20 Oct 2023 Adverse events data from a phase I trial in Solid tumours presented at the 48th European Society for Medical Oncology Congress (ESMO-2023)

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