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TP 1454

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Drug Profile

TP 1454

Alternative Names: TP-1454

Latest Information Update: 28 May 2025

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At a glance

  • Originator Tolero Pharmaceuticals
  • Developer Sumitomo Pharma America
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Pyruvate kinase stimulants; Thyroid hormone binding protein stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Solid tumours

Most Recent Events

  • 28 May 2025 No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy, First-line therapy, Late-stage disease, Metastatic disease) in USA (PO)
  • 28 May 2025 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease, Metastatic disease, Monotherapy, Second-line therapy or greater) in USA (PO)
  • 25 Apr 2025 Sumitomo Pharma Oncology completes a phase I trial in Solid tumours (Late-stage disease, Metastatic disease, Combination therapy, Monotherapy, First-line therapy) in USA (PO) (NCT04328740)

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