INCB 099280
Alternative Names: INCB-099280; INCB-99280Latest Information Update: 30 Aug 2025
At a glance
- Originator Incyte Corporation
- Developer Incyte Corporation; Mirati Therapeutics
- Class Antineoplastics; Small molecules
- Mechanism of Action Programmed cell death-1 ligand-1 inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Solid tumours; Squamous cell cancer
Most Recent Events
- 11 Jul 2025 Incyte Corporation terminates a phase I trial in Solid tumours (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA, Italy, Spain, United Kingdom due to a strategic business decision. There were no safety concerns contributing to this decision (PO) (NCT06039384)
- 06 Jun 2025 Incyte Corporation terminates a phase I/II trial in Solid tumours (Late-stage disease, Combination therapy, Second-line therapy or greater) in the United Kingdom due to a strategic business decision. There were no safety concerns contributing to this decision (PO) (NCT05949632)
- 10 Jan 2025 Phase-I development in Solid tumours is ongoing in USA, Australia, Belgium, Japan, France (PO) (NCT04242199)