ADCT 701
Alternative Names: ADCT-701; Humanized anti-DLK1 antibody ADCLatest Information Update: 16 Apr 2024
At a glance
- Originator ADC Therapeutics; Cancer Research Technology
- Developer ADC Therapeutics; National Cancer Institute (USA)
- Class Antibodies; Antineoplastics; Benzodiazepines; Drug conjugates; Immunoconjugates; Immunotoxins; Pyrroles
- Mechanism of Action DNA cross linking agents
-
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I Adrenocortical carcinoma; Neuroendocrine carcinoma; Solid tumours
Most Recent Events
- 15 Apr 2024 Phase-I clinical trials in Adrenocortical carcinoma (Metastatic disease, Late-stage disease, Second-line therapy or greater) in USA (IV) (NCT06041516)
- 15 Apr 2024 Phase-I clinical trials in Neuroendocrine carcinoma (Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV) (NCT06041516)
- 05 Apr 2024 Pharmacodynamics data from a preclinical trial in Adrenocortical carcinoma presented at the 115th Annual Meeting of the American Association for Cancer Research (AACR-2024)