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KZR 261

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Drug Profile

KZR 261

Alternative Names: KZR 834; KZR-261

Latest Information Update: 28 Oct 2024

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At a glance

  • Originator Kezar Life Sciences
  • Class Antineoplastics; Small molecules
  • Mechanism of Action SEC translocation channel inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Solid tumours
  • Discontinued Haematological malignancies

Most Recent Events

  • 28 Oct 2024 No recent reports of development identified for phase-I development in Solid-tumours(Inoperable/Unresectable, Late-stage disease, Metastatic disease) in USA (Parenteral, Injection)
  • 13 Aug 2024 Efficacy data from a phase I trial in Solid tumours released by Kezar Life Sciences
  • 13 Aug 2024 Kezar Life Sciences stops enrollment in phase-I trial in Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease) in USA (Parenteral) due to the reason that clinical resources are being reallocated toward development of zetomipzomib (NCT05047536)

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