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Barzolvolimab - Celldex Therapeutics Inc

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Drug Profile

Barzolvolimab - Celldex Therapeutics Inc

Alternative Names: Anti-KIT monoclonal antibody - Celldex Therapeutics; CDX-0159

Latest Information Update: 24 Dec 2024

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At a glance

  • Originator University of Toronto; Yale University School of Medicine
  • Developer Celldex Therapeutics Inc
  • Class Anti-inflammatories; Monoclonal antibodies; Skin disorder therapies
  • Mechanism of Action Proto-oncogene protein c-kit inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Chronic urticaria
  • Phase II Atopic dermatitis; Eosinophilic oesophagitis; Prurigo nodularis

Most Recent Events

  • 19 Dec 2024 Phase-II clinical trials in Atopic dermatitis in USA (SC) (NCT06727552)
  • 26 Oct 2024 Updated efficacy and adverse event data from a phase II trial in Chronic inducible urticaria released by Celldex Therapeutics
  • 26 Oct 2024 Celldex Therapeutics plans a phase III trial for Chronic inducible urticaria in 2025

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