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ONC 206

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Drug Profile

ONC 206

Alternative Names: ONC-206

Latest Information Update: 20 Jun 2025

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At a glance

  • Originator Oncoceutics
  • Developer Chimerix; Oncoceutics
  • Class Antineoplastics; Benzyl compounds; Imidazoles; Pyridones; Pyrimidinones; Small molecules
  • Mechanism of Action Dopamine D2 receptor antagonists; Endopeptidase Clp stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Glioma
  • Preclinical Glioblastoma; Liver cancer; Ovarian cancer; Solid tumours; Triple negative breast cancer
  • No development reported CNS cancer

Most Recent Events

  • 20 Jun 2025 Pharmacodynamics data from preclinical trial in Cancer presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 25 Apr 2025 Pharmacodynamics data from preclinical trial in Cancer presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 25 Apr 2025 Pharmacodynamics data from preclinical trial in Solid tumour presented at the 116th Annual Meeting of the American Association for Cancer Research 2025 (AACR-2025)

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