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LY 3499446

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Drug Profile

LY 3499446

Alternative Names: LY3499446

Latest Information Update: 04 Jul 2025

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At a glance

  • Originator Eli Lilly and Company
  • Class Antineoplastics
  • Mechanism of Action KRAS protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 25 Apr 2025 Pharmacodynamics data from a pre-clinical trial in Non-small cell lung cancer presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 11 Oct 2023 Pharmacodynamics data from preclinical studies in Non small cell lung cancer presented at AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics 2023 (AACR-NCI-EORTC-2023)
  • 14 Apr 2023 Pharmacodynamics data from a preclinical trial in Non small cell lung cancer presented at 114th Annual Meeting of the American Association for Cancer Research (AACR-2023)

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